The authors prospectively examined the relationship between the intake of choline/betaine and ovarian cancer risk among participants from the Nurses' Health Study (NHS) and NHSII. There were no associations between total choline, betaine, as well as choline plus betaine intake and ovarian cancer risk. Results did not vary by alcohol consumption, folate intake or after the exclusion of cases diagnosed during the 4-year period after dietary assessment.
Kotsopoulos et al (2010). "Dietary betaine and choline intake are not associated with risk of epithelial ovarian cancer." Eur J Clin Nutr 64(1): 111-114.
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