Betaine excretion correlates with plasma homocysteine when plasma lipids are elevated

OBJECTIVES: To reconcile observing a positive correlation of betaine excretion with homocysteine in lipid disorder patients but not other study groups.
DESIGN AND METHODS: Correlations were estimated in subgroups of a control group and the lipid disorder patients.
RESULTS: Plasma non high-density lipoprotein (non-HDL) cholesterol differed between the groups. The correlation increased with the median plasma non-HDL cholesterol in subgroups.
CONCLUSIONS: This correlation is associated with patients with elevated plasma lipids.

Lever, M., et al., Betaine excretion correlates with plasma homocysteine when plasma lipids are elevated. Clin Biochem, 2012. 45(1-2): p. 154-6